Models
Environmental Enteric Dysfunction
EED severity scoring, biomarker configuration, and gut health impact parameters.
4.2
Mean EED Score
/10 severity scale
42%
Elevated L:M
58%
Elevated Calprotectin
-15%
Absorption Penalty
EED Scoring Method
Select composite or single-biomarker approach
EED Score Distribution
Population distribution of composite EED severity scores (0-10)
EED Biomarker Reference
Key biomarkers, thresholds, and observed prevalence
6 rows
| Biomarker | Abbreviation | Cutoff | Prevalence (%) | Domain | Source |
|---|---|---|---|---|---|
| Lactulose:Mannitol ratio | L:M | >0.12 | 42 | Permeability | Denno et al. 2014 |
| Faecal calprotectin | FCal | >100 mcg/g | 58 | Inflammation | Campbell et al. 2017 |
| Alpha-1-antitrypsin | AAT | >27 mg/dL | 35 | Protein loss | Kosek et al. 2013 |
| Myeloperoxidase | MPO | >2000 ng/mL | 62 | Inflammation | Kosek et al. 2013 |
| Neopterin | NEO | >70 nmol/L | 48 | Immune activation | Naylor et al. 2015 |
| Reg1B | REG1B | >11 mcg/mL | 38 | Intestinal damage | Arndt et al. 2016 |